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The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro

Lechler, Philipp and Renkawitz, Tobias and Campean, Valentina and Balakrishnan, Sanjeevi and Tingart, Markus and Grifka, Joachim and Schaumburger, Jens (2011) The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro. BMC Cancer 11, p. 120.

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Abstract

Background Chondrosarcoma is virtually resistant to chemotherapy and radiation therapy. Survivin, the smallest member of the inhibitor of apoptosis protein family, is a critical factor for tumor progression and resistance to conventional therapeutic approaches in a wide range of malignancies. However, the role of survivin in chondrosarcoma has not been well studied. We examined the importance of ...

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Item Type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Orthopädie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/1471-2407-11-120DOI
21457573PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Universitätsbibliothek Regensburg
Deposited On:25 May 2011 09:59
Last Modified:13 Mar 2014 17:25
Item ID:20976
Owner Only: item control page

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