Urbaschek, R. and Männel, Daniela N. and Urbanczik, R. (1991) Isoniazid protects mice against endotoxin lethality without influencing tumor necrosis factor synthesis and release. Antimicrobial agents and chemotherapy 35 (8), pp. 1666-1668.
Treatment of NMRI mice with isoniazid (INH; 25 mg/kg) intraperitoneally induced significant protection when it was injected before or after a lethal intravenous challenge with endotoxin. The INH preparation used was not contaminated with endotoxin. Tumor necrosis factor (TNF) was not elevated in sera from NMRI mice 2 h after the injection of INH. INH did not influence TNF synthesis or release ...
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|Institutions:||Medicine > Lehrstuhl für Immunologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 Jun 2011 05:59|
|Last Modified:||13 Mar 2014 17:33|