Hass, R. and Lonnemann, G. and Männel, Daniela N. and Topley, N. and Hartmann, A. and Köhler, L. and Resch, K. and Goppelt-Strübe, M.
Regulation of TNF-alpha, IL-1 and IL-6 synthesis in differentiating human monoblastoid leukemic U937 cells.
Leukemia research 15 (5), pp. 327-339.
The human monoblastoid tumor cell line U937 was induced to differentiate along the monocyte/macrophage lineage by treatment with 5 x 10(-9) M 12-O-tetradecanoyl phorbol-13-acetate (TPA). Between 2 h and 4 h following TPA-treatment U937 cells started to release significant amounts of TNF-alpha which remained detectable until 8-10 days. A significant IL-1 beta release was measured 24 h-48 h post ...
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|Institutions:||Medicine > Lehrstuhl für Immunologie|
|Cell Differentiation/drug effects||MESH|
|Leukemia, Monocytic, Acute||MESH|
|Tumor Necrosis Factor-alpha/pharmacology||MESH|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||20 Jun 2011 06:18|
|Last Modified:||13 Mar 2014 17:33|