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Tumour necrosis factor production and natural killer cell activity in peripheral blood during treatment with recombinant tumour necrosis factor

Männel, Daniela N. and Kist, A. and Ho, A. D. and Räth, U. and Reichardt, P. and Wiedenmann, B. and Schlick, E. and Kirchner, H. (1989) Tumour necrosis factor production and natural killer cell activity in peripheral blood during treatment with recombinant tumour necrosis factor. British journal of cancer 60 (4), pp. 585-588.

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Abstract

Tumour necrosis factor (TNF) has been found to be an important immunomodulator. Among other functions TNF activates natural killer (NK) cells and stimulates monocytes/macrophages in an autocrine fashion. TNF production and NK activity in peripheral blood mononuclear cells were determined in a clinical phase I study in which recombinant human (rh) TNF was administered as a continuous infusion ...

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Item Type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
2803928PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
Colorectal Neoplasms/therapyMESH
FemaleMESH
HumansMESH
Killer Cells, Natural/drug effectsMESH
MaleMESH
Middle AgedMESH
Recombinant Proteins/therapeutic useMESH
Tumor Necrosis Factor-alpha/therapeutic useMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jun 2011 06:24
Last Modified:13 Mar 2014 17:33
Item ID:21175
Owner Only: item control page
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