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Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins

Flegel, W. A. and Wölpl, A. and Männel, Daniela N. and Northoff, H. (1989) Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins. Infection and immunity 57 (7), pp. 2237-2245.

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Abstract

Toxicity of lipopolysaccharide (LPS) (endotoxin) is, to a large extent, mediated by the activation of monocytes/macrophages and subsequent release of monokines, such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-alpha). It is known that LPS binds readily to serum lipoproteins and that LPS-lipoprotein complexes are less toxic than unbound LPS. Here we present data analyzing the ...

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Item Type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
2731990PubMed ID
Classification:
NotationType
Antibodies, Bacterial/physiologyMESH
Cholesterol/bloodMESH
Complement System Proteins/physiologyMESH
Dietary Fats/bloodMESH
EndotoxinsMESH
Fatty Acids/bloodMESH
HumansMESH
Immunosuppressive Agents/physiologyMESH
KineticsMESH
Lipopolysaccharides/immunologyMESH
Lipoproteins/physiologyMESH
Macrophage ActivationMESH
TemperatureMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jun 2011 06:23
Last Modified:13 Mar 2014 17:33
Item ID:21177
Owner Only: item control page
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