Startseite UB

Decrease of natural killer cell activity and monokine production in peripheral blood of patients treated with recombinant tumor necrosis factor

Kist, A. and Ho, A. D. and Räth, U. and Wiedenmann, B. and Bauer, A. and Schlick, E. and Kirchner, H. and Männel, Daniela N. (1988) Decrease of natural killer cell activity and monokine production in peripheral blood of patients treated with recombinant tumor necrosis factor. Blood 72 (1), pp. 344-348.

[img]
Preview
PDF
Download (996kB)

at PubMed


Abstract

Tumor necrosis factor (TNF), a protein predominantly produced by activated macrophages/monocytes, is presently available in recombinant, purified form for clinical trials. Intensive studies in many laboratories have shown that besides the tumorcytotoxic effects, TNF acts on a large array of different cells and has potent immunomodulatory activities. In a clinical phase I study, some immunologic ...

plus


Export bibliographical data

Item Type:Article
Date:1988
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
2968823PubMed ID
Classification:
NotationType
AdultMESH
Concanavalin AMESH
Cytotoxicity, Immunologic/drug effectsMESH
Drug EvaluationMESH
FemaleMESH
HumansMESH
Immunosuppressive Agents/administration & dosageMESH
Infusions, IntravenousMESH
Interleukin-1/biosynthesisMESH
Killer Cells, Natural/immunologyMESH
Lymphocyte Activation/drug effectsMESH
MaleMESH
Middle AgedMESH
Neoplasms/immunologyMESH
PhytohemagglutininsMESH
Receptors, Fc/analysisMESH
Receptors, IgGMESH
Recombinant Proteins/administration & dosageMESH
Tumor Necrosis Factor-alpha/administration & dosageMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jun 2011 06:14
Last Modified:13 Mar 2014 17:34
Item ID:21180
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact