Hensel, G. and Männel, Daniela N. and Pfizenmaier, K. and Krönke, M. (1987) Autocrine stimulation of TNF-alpha mRNA expression in HL-60 cells. Lymphokine research 6 (2), pp. 119-125.
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We have employed a human promyelocytic leukemic cell line, HL-60, to investigate the conditions that regulate TNF-alpha gene expression in vitro. Using a cloned TNF-alpha specific cDNA probe, we show by Northern blot analysis that TNF-alpha mRNA rapidly accumulates in HL-60 cells following treatment with phorbol myristate acetate (PMA). TNF-alpha mRNA levels peak at 1-2 hours and then decline to ...
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|Institutions:||Medicine > Lehrstuhl für Immunologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||22 Jun 2011 08:16|
|Last Modified:||22 Oct 2012 09:47|