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Separation of a serum-derived tumoricidal factor from a helper factor for plaque-forming cells

Männel, Daniela N. and Farrar, J. J. and Mergenhagen, S. E. (1980) Separation of a serum-derived tumoricidal factor from a helper factor for plaque-forming cells. Journal of immunology 124 (3), pp. 1106-1110.

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Abstract

C3H/HeN mice administered BCG followed by lipopolysaccharide 14 days later released into their serum a cytotoxic factor for tumor cells and a factor that restored the anti-SRBC plaque-forming cell response of nude mouse spleen cells (helper activity). Gel filtration of serum containing the cytotoxic and the helper activities indicated that both factors exhibited an apparent m.w. of 125,000 to ...

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Item Type:Article
Date:1980
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
6987307PubMed ID
Classification:
NotationType
AnimalsMESH
Antibody-Producing Cells/immunologyMESH
Chemical PrecipitationMESH
Chromatography, GelMESH
Cytotoxicity, ImmunologicMESH
FemaleMESH
L Cells (Cell Line)/immunologyMESH
Lipopolysaccharides/pharmacologyMESH
Lymphocyte ActivationMESH
MaleMESH
MiceMESH
Mice, Inbred C3HMESH
Mice, NudeMESH
Molecular WeightMESH
Mycobacterium bovis/immunologyMESH
T-Lymphocytes/immunologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Jun 2011 06:21
Last Modified:13 Mar 2014 17:33
Item ID:21208
Owner Only: item control page

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