Startseite UB

Nucleosomes protect DNA from DNA methylation in vivo and in vitro

Felle, Max and Hoffmeister, Helen and Rothammer, Julia and Fuchs, Andreas and Exler, Josef H. and Längst, Gernot (2011) Nucleosomes protect DNA from DNA methylation in vivo and in vitro. Nucleic Acids Research 39, p. 6956.

[img]
Preview
License: Creative Commons Attribution Non-commercial
PDF - Published Version
Download (4MB)

at publisher (via DOI)


Abstract

Positioned nucleosomes limit the access of proteins to DNA. However, the impact of nucleosomes on DNA methylation in vitro and in vivo is poorly understood. Here, we performed a detailed analysis of nucleosome binding and nucleosomal DNA methylation by the de novo methyltransferases. We show that compared to linker DNA, nucleosomal DNA is largely devoid of CpG methylation. ATP-dependent chromatin ...

plus


Export bibliographical data



Item Type:Article
Date:2011
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1093/nar/gkr263DOI
Keywords:Gene Regulation, Chromatin and Epigenetics
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Jul 2011 08:03
Last Modified:13 Mar 2014 17:47
Item ID:21623
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact