Startseite UB

Effect of amodiaquine on gastric histamine methyltransferase and on histamine-stimulated gastric secretion

Barth, H. and Lorenz, Wilfried and Troidl, H. (1975) Effect of amodiaquine on gastric histamine methyltransferase and on histamine-stimulated gastric secretion. British journal of pharmacology 55 (3), pp. 321-327.

[img]
Preview
PDF
Download (971kB)

at PubMed


Abstract

1 Amodiaquine was found to be a potent inhibitor in vitro of gastric histamine methyltransferase from human and canine corpus and from pig antrum. The ID50 for the enzyme, purified from pig antrum mucosa by ultracentrifugation and chromatography on DEAE-cellulose, was 2.5 muM. 2 In six dogs with Heidenhanin pouches the maximum secretory response to histamine (40 mug/kg i.m.) was augmented by i.m. ...

plus


Export bibliographical data



Item Type:Article
Date:1975
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
4150326PubMed ID
Classification:
NotationType
Amodiaquine/pharmacologyMESH
AnimalsMESH
Betazole/pharmacologyMESH
DogsMESH
Gastric Mucosa/secretionMESH
Histamine/pharmacologyMESH
Histamine N-Methyltransferase/antagonists & inhibitorsMESH
HumansMESH
Methyltransferases/antagonists & inhibitorsMESH
Stimulation, ChemicalMESH
Stomach/enzymologyMESH
SwineMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:23 Aug 2011 06:32
Last Modified:13 Mar 2014 17:52
Item ID:21880
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact