Barth, H. and Lorenz, Wilfried and Troidl, H. (1975) Effect of amodiaquine on gastric histamine methyltransferase and on histamine-stimulated gastric secretion. British journal of pharmacology 55 (3), pp. 321-327.
1 Amodiaquine was found to be a potent inhibitor in vitro of gastric histamine methyltransferase from human and canine corpus and from pig antrum. The ID50 for the enzyme, purified from pig antrum mucosa by ultracentrifugation and chromatography on DEAE-cellulose, was 2.5 muM. 2 In six dogs with Heidenhanin pouches the maximum secretory response to histamine (40 mug/kg i.m.) was augmented by i.m. ...
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|Institutions:||Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||23 Aug 2011 06:32|
|Last Modified:||13 Mar 2014 17:52|