Deutsch
He, Shuying and Pirity, Melinda K. and Wang, Wei-Lin and Wolf, Louise and Chauhan, Bharesh K. and Cveklova, Kveta and Tamm, Ernst R. and Ashery-Padan, Ruth and Metzger, Daniel and Nakai, Akira and Chambon, Pierre and Zavadil, Jiri and Cvekl, Ales (2010) Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics & chromatin 3 (1), p. 21.
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Abstract
These studies demonstrate a cell-autonomous role for Brg1 in lens fiber cell terminal differentiation and identified DNase IIβ as a potential direct target of SWI/SNF complexes. Brg1 is directly or indirectly involved in processes that degrade lens fiber cell chromatin. The presence of nuclei and other organelles generates scattered light incompatible with the optical requirements for the lens.
| Item Type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Institutions: | Medicine > Lehrstuhl für Humangenetik | ||||||
| Identification Number: |
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| Subjects: | 600 Technology > 610 Medical sciences Medicine | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Unknown | ||||||
| Owner: | Universitätsbibliothek Regensburg | ||||||
| Deposited On: | 26 Sep 2011 11:46 | ||||||
| Last Modified: | 26 Sep 2011 11:46 | ||||||
| Item ID: | 22189 |
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