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Evolution and functional divergence of the anoctamin family of membrane proteins

Milenkovic, Vladimir M. and Brockmann, Marisa and Stöhr, Heidi and Weber, Bernhard H. F. and Strauss, Olaf (2010) Evolution and functional divergence of the anoctamin family of membrane proteins. BMC evolutionary biology 10, p. 319.

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Abstract

Our study suggests that anoctamins have evolved by series of duplication events, and that they are constrained by purifying selection. In addition we identified a number of protein domains, and amino acid residues which contribute to predicted functional divergence. Hopefully, this work will facilitate future functional characterization of the anoctamin membrane protein ...

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Item Type:Article
Date:2010
Institutions:Medicine > Lehrstuhl für Augenheilkunde
Identification Number:
ValueType
20964844PubMed ID
10.1186/1471-2148-10-319DOI
Classification:
NotationType
Chloride Channels/geneticsMESH
Computational BiologyMESH
Evolution, MolecularMESH
Likelihood FunctionsMESH
Membrane Proteins/geneticsMESH
Neoplasm Proteins/geneticsMESH
PhylogenyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Sep 2011 09:51
Last Modified:13 Mar 2014 18:03
Item ID:22195
Owner Only: item control page

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