Milenkovic, Vladimir M. and Brockmann, Marisa and Stöhr, Heidi and Weber, Bernhard H. F. and Strauss, Olaf (2010) Evolution and functional divergence of the anoctamin family of membrane proteins. BMC evolutionary biology 10, p. 319.
Our study suggests that anoctamins have evolved by series of duplication events, and that they are constrained by purifying selection. In addition we identified a number of protein domains, and amino acid residues which contribute to predicted functional divergence. Hopefully, this work will facilitate future functional characterization of the anoctamin membrane protein family.
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|Institutions:||Medicine > Lehrstuhl für Augenheilkunde|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||26 Sep 2011 09:51|
|Last Modified:||13 Mar 2014 18:03|