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The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro

Lechler, Philipp and Balakrishnan, Sanjeevi and Schaumburger, Jens and Grässel, Susanne and Baier, Clemens and Grifka, Joachim and Straub, Rainer H. and Renkawitz, Tobias (2011) The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC musculoskeletal disorders 12, p. 150.

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Abstract

Background Regulation of cell death and cell division are key processes during chondrogenesis and in cartilage homeostasis and pathology. The oncogene survivin is considered to be critical for the coordination of mitosis and maintenance of cell viability during embryonic development and in cancer, and is not detectable in most adult differentiated tissues and cells. We analyzed survivin ...

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Item Type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Orthopädie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
21729321PubMed ID
10.1186/1471-2474-12-150DOI
Keywords:apoptosis; chondrocyte; osteoarthritis; proliferation; survivin
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Universitätsbibliothek Regensburg
Deposited On:19 Oct 2011 13:35
Last Modified:13 Mar 2014 18:06
Item ID:22421
Owner Only: item control page

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