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Sulfated β-(1→4)-galacto-oligosaccharides and their effect on angiogenesis

Käsbauer, C. W. and Paper, D. H. and Franz, Gerhard (2001) Sulfated β-(1→4)-galacto-oligosaccharides and their effect on angiogenesis. Carbohydrate research 330 (3), pp. 427-430.

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Abstract

Sulfated β-(1→4)-galacto-oligosaccharides were prepared from an arabino-galacto-rhamno-galacturonan from Lupinus polyphyllus Lindl. by successive partial hydrolysis and SO3–pyridine sulfation in DMF. The resulting oligosaccharide polysulfates were analyzed by analytical GPC and the sulfate content was determined by ion chromatography. DP 5 and higher showed a pronounced antiangiogenic effect with ...

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Item Type:Article
Date:2001
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz
Identification Number:
ValueType
11270823PubMed ID
Classification:
NotationType
Allantois/blood supplyMESH
Angiogenesis Inhibitors/pharmacologyMESH
AnimalsMESH
Carbohydrate ConformationMESH
Carbohydrate SequenceMESH
Chick EmbryoMESH
Chorion/blood supplyMESH
Fabaceae/chemistryMESH
Molecular Sequence DataMESH
Neovascularization, Physiologic/drug effectsMESH
Oligosaccharides/pharmacologyMESH
Plants, MedicinalMESH
Polysaccharides/isolation & purificationMESH
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:21 Nov 2011 10:32
Last Modified:21 Nov 2011 10:32
Item ID:22620
Owner Only: item control page
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