Bode, V. and Welzel, D. and Franz, Gerhard and Polensky, U. (1990) Absence of drug interaction between heparin and nitroglycerin. Randomized placebo-controlled crossover study. Archives of Internal Medicine 150 (10), pp. 2117-2119.
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The purpose of this randomized crossover study was to determine whether nitroglycerin interacts with heparin in terms of its anticoagulative properties as determined by activated partial thromboplastin time and thrombin time. Eight healthy adults were given either a 60-minute intravenous infusion of 5 mg of nitroglycerin or a 0.9% sodium chloride solution subsequent to the administration of an intravenous injection of 5000 U of heparin. No nitroglycerin-related drug interference with heparin was observed as measured by the activated partial thromboplastin time and the thrombin time.
|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||25 Nov 2011 09:38|
|Last Modified:||25 Nov 2011 09:38|