Becker, Markus and Franz, Gerhard and Alban, Susanne (2003) Inhibition of PMN-elastase activity by semisynthetic glucan sulfates. Thrombosis and Haemostasis 89, pp. 915-925.
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Proteolysis of connective tissue by enzymes such as PMN-elastase(PMNE) is a crucial step during inflammation and metastasis.Semisynthetic sulfated carbohydrates (SC) were shown toexhibit potent antiinflammatory and antimetastatic activity invivo. The aim of the present study was to examine whetherinterferences with PMN-elastase may contribute to theseeffects. Therefore, the interactions of these ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Franz|
|Keywords:||PMN-elastase, glucan sulfates, heparin, inflammation, metastasis|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||01 Dec 2011 11:38|
|Last Modified:||01 Dec 2011 11:38|