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Post-translational modification and regulation of human Spir protein

URN to cite this document: urn:nbn:de:bvb:355-epub-229606

Lakshmi, Sreeja (2011) Post-translational modification and regulation of human Spir protein. PhD, Universität Regensburg

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Abstract (English)

Spir proteins are the primodial members of the emerging group of actin nucleation factors, which initiate actin polymerization by binding monomeric actin to one or multiple Wiskott-Aldrich Syndrome protein (WASp) homology-2 domains. Spir proteins are implicated in diverse cellular processes including actin dynamics, vesicle trafficking as well as Drosophila and mammalian oogenesis. Despite the ...

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Translation of the abstract (German)

Spir Proteine sind primodiale Elemente einer neuen Gruppe von Aktin-Nukleations-Faktoren, die Aktin Polymerisation initiieren, indem sie Aktin Monomere an ein oder mehrere Wiskott- Aldrich-Syndrom Protein Homologie-2 Domänen (WASp) binden. Spir Proteine werden mit diversen zellulären Prozessen in Verbindung gebracht, einschließlich Aktin-Dynamik, Vesikel-Transport und Oogenese in Drosophila und ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:14 December 2011
Referee:Prof. Dr. Eugen Kerkhoff
Date of exam:13 December 2011
Institutions:Medicine > Lehrstuhl für Neurologie
Keywords:Actin dynamics, Spir, post-translational modification, Mass spectrometry
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Dec 2011 10:33
Last Modified:13 Mar 2014 18:18
Item ID:22960
Owner Only: item control page
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