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Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics

Brandl, Ferdinand and Kastner, Fritz and Gschwind, R. M. and Blunk, Torsten and Teßmar, Jörg and Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), pp. 221-228.

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Abstract

Hydrogels are extensively studied as matrices for the controlled release of macromolecules. To evaluate the mobility of embedded molecules, these drug delivery systems are usually characterized by release studies. However, these experiments are time-consuming and their reliability is often poor. In this study, gels were prepared by step-growth polymerization of poly(ethylene glycol) (PEG) and ...

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Item Type:Article
Date:2010
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. Ruth Gschwind
Identification Number:
ValueType
10.1016/j.jconrel.2009.10.030DOI
Keywords:Hydrogel; Drug delivery; Fluorescence recovery after photobleaching; Release study; Diffusion coefficient
Subjects:500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Dr. Ferdinand Brandl
Deposited On:23 Jan 2012 14:11
Last Modified:23 Jan 2012 14:11
Item ID:23232
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