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Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells

Wenzel-Seifert, Katharina and Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), pp. 298-316.

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Abstract

Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins). We investigated the role of extracellular nucleotides in the regulation of beta-glucuronidase release in HL-60 cells. In dibutyryl cyclic AMP (Bt2cAMP)-differentiated HL-60 cells, the ...

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Item Type:Article
Date:1990
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
1966023PubMed ID
Classification:
NotationType
Bucladesine/pharmacologyMESH
Calcium/metabolismMESH
Cell Differentiation/drug effectsMESH
Cytochalasin B/pharmacologyMESH
Exocytosis/physiologyMESH
Glucuronidase/secretionMESH
HumansMESH
Leukemia/physiopathologyMESH
N-Formylmethionine Leucyl-Phenylalanine/pharmacologyMESH
Nucleotides/pharmacologyMESH
Phorbol Esters/pharmacologyMESH
Superoxides/metabolismMESH
Tumor Cells, Cultured/physiologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:24 Jan 2012 13:37
Last Modified:13 Mar 2014 18:33
Item ID:23242
Owner Only: item control page

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