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Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol

Seifert, Roland and Schächtele, C. and Rosenthal, W. and Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), pp. 20-26.

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Abstract

Both cis- and trans-unsaturated but not saturated fatty acids activated protein kinase C purified to apparent homogeneity from rat brain. Fatty-acid-induced enzyme activation was not more than additive with that by phospholipids and was potentiated by diacylglycerol. Recently, we demonstrated that cis- and trans-unsaturated fatty acids induced platelet aggregation and phosphorylation of specific ...

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Item Type:Article
Date:1988
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
3395325PubMed ID
Classification:
NotationType
AnimalsMESH
Brain/enzymologyMESH
Calcium/pharmacologyMESH
Diglycerides/pharmacologyMESH
Enzyme ActivationMESH
Fatty Acids, Unsaturated/pharmacologyMESH
Glycerides/pharmacologyMESH
KineticsMESH
Protein Kinase C/metabolismMESH
RatsMESH
StereoisomerismMESH
Structure-Activity RelationshipMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:24 Jan 2012 13:07
Last Modified:13 Mar 2014 18:29
Item ID:23266
Owner Only: item control page

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