Startseite UB

Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol

Seifert, Roland and Schächtele, C. and Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), pp. 762-768.

[img]
Preview
PDF
Download (582kB)

at PubMed


Abstract

Octadecadienoic acids (linoleic acid and linolelaidic acid) and the diacylglycerol, 1-oleoyl-2-acetyl-rac-glycerol (OAG) concentration-dependently induced activation of gel-filtered human platelets, i.e. aggregation and phosphorylation of 20 kDa and 47 kDa peptides. In contrast, octadecenoic acids (oleic and elaidic acid) and octadecanoic (stearic) acid were inactive. Octadecadienoic acid-induced ...

plus


Export bibliographical data



Item Type:Article
Date:1987
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
3426598PubMed ID
Classification:
NotationType
Blood Platelets/enzymologyMESH
Diglycerides/pharmacologyMESH
Enzyme Activation/drug effectsMESH
Glycerides/pharmacologyMESH
HumansMESH
PhosphorylationMESH
Platelet Aggregation/drug effectsMESH
Protein Kinase C/analysisMESH
Proteins/metabolismMESH
Stearic Acids/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Jan 2012 08:31
Last Modified:13 Mar 2014 18:29
Item ID:23271
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact