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Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils

Seifert, Roland and Rosenthal, W. and Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), pp. 161-165.

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Abstract

In the chain of events by which chemotactic peptides stimulate NADPH oxidase-catalyzed superoxide formation in human neutrophils, the involvements of a pertussis toxin-sensitive guanine nucleotide-binding protein (N-protein), mobilization of intracellular calcium and protein kinase C stimulation have been proposed. Superoxide formation was studied in membranes from human neutrophils; NADPH ...

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Item Type:Article
Date:1986
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
3017756PubMed ID
Classification:
NotationType
Cell Membrane/enzymologyMESH
Enzyme Activation/drug effectsMESH
Guanine Nucleotides/pharmacologyMESH
Guanosine 5'-O-(3-Thiotriphosphate)MESH
Guanosine Triphosphate/pharmacologyMESH
HumansMESH
NADH, NADPH Oxidoreductases/bloodMESH
NADPH OxidaseMESH
Neutrophils/enzymologyMESH
Superoxides/bloodMESH
Thionucleotides/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Jan 2012 08:30
Last Modified:13 Mar 2014 18:30
Item ID:23282
Owner Only: item control page

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