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Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells

Musgrave, I. F. and Seifert, Roland and Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, pp. 437-441.

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Abstract

We investigated whether maitotoxin activates non-selective cation channels, as was recently proposed [Soergel, Yasumoto, Daly and Gusovsky (1992) Mol. Pharmacol. 41, 487-493]. Stimulation of dibutyryl cyclic AMP-differentiated HL-60 cells with the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP; 0.1 microM), the Ca(2+)-ATPase inhibitor thapsigargin (0.1 microM) or ...

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Item Type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
7519011PubMed ID
Classification:
NotationType
Bucladesine/pharmacologyMESH
Cadmium/pharmacologyMESH
Calcium/metabolismMESH
CationsMESH
Fluorescent DyesMESH
Fura-2MESH
Gadolinium/pharmacologyMESH
HumansMESH
Imidazoles/pharmacologyMESH
Ion Channels/drug effectsMESH
Manganese/pharmacologyMESH
Marine Toxins/pharmacologyMESH
N-Formylmethionine Leucyl-Phenylalanine/pharmacologyMESH
OxocinsMESH
Terpenes/pharmacologyMESH
Tetradecanoylphorbol Acetate/pharmacologyMESH
ThapsigarginMESH
Tumor Cells, CulturedMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Jan 2012 08:24
Last Modified:13 Mar 2014 18:30
Item ID:23297
Owner Only: item control page

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