Startseite UB

Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets

Berger, M. and Offermanns, S. and Seifert, Roland and Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

[img]
Preview
PDF
Download (2MB)

at PubMed


Abstract

Lipopeptide analogues of the NH2-terminus of bacterial lipoprotein are known to induce activation of macrophages, neutrophils, and lymphocytes. We studied the effect of the lipopeptide N-palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-(R)-cysteinyl-( S)-seryl-(S)-lysyl-(S)-lysyl-(S)-lysyl-(S)-lysine [Pam3CysSer(Lys)4] on several functions of human platelets. Pam3CysSer(Lys)4 led to the ...

plus


Export bibliographical data



Item Type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
8023898PubMed ID
Classification:
NotationType
Blood Platelets/drug effectsMESH
Calcium/metabolismMESH
Dose-Response Relationship, DrugMESH
Epoprostenol/pharmacologyMESH
GenisteinMESH
HumansMESH
Intracellular Membranes/metabolismMESH
Isoflavones/pharmacologyMESH
Lipoproteins/pharmacologyMESH
Osmolar ConcentrationMESH
Phosphorylation/drug effectsMESH
Platelet ActivationMESH
Platelet AggregationMESH
Protein-Tyrosine Kinases/antagonists & inhibitorsMESH
Receptors, EpoprostenolMESH
Receptors, Prostaglandin/antagonists & inhibitorsMESH
Serotonin/metabolismMESH
Tyrosine/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:26 Jan 2012 08:22
Last Modified:13 Mar 2014 18:30
Item ID:23298
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact