Pelucchi, Bruna and Aguiari, Gianluca and Pignatelli, Angela and Manzati, Elisa and Witzgall, Ralph and Senno, Laura del and Belluzzi, Ottorino (2006) Nonspecific Cation Current Associated with Native Polycystin-2 in HEK-293 Cells. Journal of the American Society of Nephrology - JASN 17 (2), pp. 388-397.
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Mutations in either PKD1 or PKD2 gene are associated with autosomal dominant polycystic kidney disease, the most common inherited kidney disorder. Polycystin-2 (PC2), the PKD2 gene product, and the related protein polycystin-L, function as Ca2+-permeable, nonselective cation channels in different expression systems. This work describes a nonspecific cation current (ICC) that is present in native ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Anatomie|
|Dewey Decimal Classification:||500 Science > 570 Life sciences|
600 Technology > 610 Medical sciences Medicine
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited on:||02 Aug 2006|
|Last modified:||25 Jul 2011 08:20|