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Occlusion of regulatory sequences by promoter nucleosomes in vivo

Mao, Changhui and Brown, Christopher R. and Griesenbeck, Joachim and Boeger, Hinrich (2011) Occlusion of regulatory sequences by promoter nucleosomes in vivo. PloS one 6 (3), e17521.

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Abstract

Nucleosomes are believed to inhibit DNA binding by transcription factors. Theoretical attempts to understand the significance of nucleosomes in gene expression and regulation are based upon this assumption. However, nucleosomal inhibition of transcription factor binding to DNA is not complete. Rather, access to nucleosomal DNA depends on a number of factors, including the stereochemistry of ...

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Item Type:Article
Date:2011
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Joachim Griesenbeck
Identification Number:
ValueType
21408617PubMed ID
10.1371/journal.pone.0017521DOI
Classification:
NotationType
Base SequenceMESH
DNA, Fungal/metabolismMESH
Gene DeletionMESH
Gene Expression Regulation, FungalMESH
Genetic LinkageMESH
Mutation/geneticsMESH
Nucleosomes/metabolismMESH
Promoter Regions, GeneticMESH
Protein BindingMESH
Saccharomyces cerevisiae/geneticsMESH
Saccharomyces cerevisiae Proteins/metabolismMESH
TATA-Box Binding Protein/metabolismMESH
Transcriptional Activation/geneticsMESH
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:17 Feb 2012 08:39
Last Modified:13 Mar 2014 18:37
Item ID:23457
Owner Only: item control page
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