Milenkovic, Vladimir M. and Krejcova, Sarka and Reichhart, Nadine and Wagner, Andrea and Strauss, Olaf (2011) Interaction of bestrophin-1 and Ca2+ channel β-subunits: identification of new binding domains on the bestrophin-1 C-terminus. PloS one 6 (4), e19364.
Bestrophin-1 modulates currents through voltage-dependent L-type Ca(2+) channels by physically interacting with the β-subunits of Ca(2+) channels. The main function of β-subunits is to regulate the number of pore-forming Ca(V)-subunits in the cell membrane and modulate Ca(2+) channel currents. To understand the influence of full-length bestrophin-1 on β-subunit function, we studied binding and ...
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|Date:||29 April 2011|
|Institutions:||Medicine > Lehrstuhl für Augenheilkunde|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||11 Apr 2012 09:07|
|Last Modified:||13 Mar 2014 18:45|