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PI3K-dependent GSK3ß(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response.

Karrasch, Thomas and Spaeth, Tanja and Allard, Brigitte and Jobin, Christian (2011) PI3K-dependent GSK3ß(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response. PloS one 6 (10), e26340.

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Abstract

We conclude that PI3K-mediated GSK3ß phosphorylation is involved in the intestinal epithelial wound-healing response. Phosphorylation of GSK3ß may be important for intestinal restitution by promoting cell motility in response to ...

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Item Type:Article
Date:19 October 2011
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
22039465PubMed ID
10.1371/journal.pone.0026340DOI
Classification:
NotationType
AnimalsMESH
Base SequenceMESH
Blotting, WesternMESH
Cell LineMESH
DNA PrimersMESH
Glycogen Synthase Kinase 3/metabolismMESH
Intestinal Mucosa/pathologyMESH
MiceMESH
Mice, KnockoutMESH
Phosphatidylinositol 3-Kinases/metabolismMESH
PhosphorylationMESH
Protein TransportMESH
RatsMESH
Real-Time Polymerase Chain ReactionMESH
Serine/metabolismMESH
Signal TransductionMESH
Wound HealingMESH
beta Catenin/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:11 Apr 2012 09:01
Last Modified:13 Mar 2014 18:45
Item ID:23755
Owner Only: item control page
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