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Improving the biocompatibility of titanium- and cobalt-based biomaterials by covalent immobilization of crosslinked collagen

Müller, Rainer and Heckmann, Klaus and Angele, Peter and Kujat, R. and Nerlich, Michael (2007) Improving the biocompatibility of titanium- and cobalt-based biomaterials by covalent immobilization of crosslinked collagen. In: Breme, Jürgen, (ed.) Metallic Biomaterial Interfaces. Wiley-VCH, Weinheim, pp. 88-92. ISBN 978-3-527-31860-5.

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Abstract

The surfaces of titanium- and cobalt-based biomaterials with layers of fibrillar type-I collagen were coated to enhance initial osteoblast adhesion and implant-tissue integration. The coating procedure for biofunctionalization of metallic implant materials was presented. Surface d. of amino groups was elevated which resulted to a higher d. of covalent linkages which improved the stability of ...

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Export bibliographical data

Item Type:Book Section
Date:2007
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Keywords:titanium cobalt biomaterial biocompatibility covalent immobilization crosslinked collagen
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Georg Berger
Deposited On:19 Jun 2012 06:33
Last Modified:19 Jun 2012 06:33
Item ID:24942
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