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Parallel solid-phase synthesis of diaryltriazoles

Wrobel, Matthias and Aube, Jeffrey and König, Burkhard (2012) Parallel solid-phase synthesis of diaryltriazoles. Beilstein Journal of Organic Chemistry (8), pp. 1027-1036.

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Abstract

A series of substituted diaryltriazoles was prepared by a solid-phase-synthesis protocol using a modified Wang resin. The copper(I)- or ruthenium(II)-catalyzed 1,3-cycloaddition on the polymer bead allowed a rapid synthesis of the target compounds in a parallel fashion with in many cases good to excellent yields. Substituted diaryltriazoles resemble a molecular structure similar to established ...

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Item Type:Article
Date:2012
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Identification Number:
ValueType
10.3762/bjoc.8.115DOI
Keywords:chemical diversity; Huisgen cycloaddition; library synthesis; peptidomimetics; solid phase synthesis; triazole
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:12 Jul 2012 06:19
Last Modified:12 Jul 2012 06:19
Item ID:25347
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