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Untersuchung molekularer Therapie-Response-Marker bei lokal fortgeschrittenen Harnblasenkarzinomen mit adjuvanter Chemotherapie

URN to cite this document: urn:nbn:de:bvb:355-epub-255551

Leicht, Christina (2012) Untersuchung molekularer Therapie-Response-Marker bei lokal fortgeschrittenen Harnblasenkarzinomen mit adjuvanter Chemotherapie. PhD, Universität Regensburg

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Abstract (German)

Grundlage dieser Arbeit war das Datenmaterial von 327 Patienten, welche alle an einem invasiven Harnblasenkarzinom erkrankt waren und eine adjuvante Chemotherapie erhalten hatten. Aus den paraffineingebetteten Tumorgewebeproben wurden sogenannte Tissue Microarrays hergestellt, welche im Anschluss immunhistochemisch untersucht worden sind. Es konnte nachgewiesen werden, dass ein signifikanter ...

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Translation of the abstract (English)

Basis of this study was the data of 327 patients, which were diagnosed with invasive bladder cancer and received adjuvant chemotherapy. Tissue microarrays were constructed to study the immunohistochemical expression of Emmprin, p53, BAX, and BCL2. It was demonstrated that there is a significant correlation between positive lymph node status and survival. Also a blood vessel invasion of the tumor ...

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Export bibliographical data



Item Type:Thesis of the University of Regensburg (PhD)
Date:16 August 2012
Referee:Prof. Dr. Arndt Hartmann
Date of exam:31 July 2012
Institutions:Medicine > Lehrstuhl für Pathologie
Research groups and research centres:Not selected
Keywords:Urothelkarzinom, Harnblasenkarzinom, Tissue-Mikroarray, Emmprin, molekulare Prognosemarker, Tumormarker, Prognose, adjuvante Chemotherapie, bladder cancer, tissue microarray, Emmprin, molecular markers, prognostic indicators, adjuvant chemotherapy
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:16 Aug 2012 07:13
Last Modified:13 Mar 2014 19:05
Item ID:25555
Owner Only: item control page

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