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Fischer Indole Synthesis in Low Melting Mixtures

Gore, Sangram and Baskaran, Sundarababu and König, Burkhard (2012) Fischer Indole Synthesis in Low Melting Mixtures. Organic Letters 14 (17), pp. 4568-4571.

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Abstract

Functionalized indoles are synthezised under mild conditions in a tartaric acid-dimethylurea melt. The melt serves as the solvent and as the catalyst. Under these reaction conditions, sensitive functional groups such as N-Boc, N-Cbz, or azides are stable, and indolenines are obtained regioselectively in excellent yields. The practical use of the method is demonstrated in the synthesis of the ...

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Item Type:Article
Date:2012
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:Indigo
Identification Number:
ValueType
10.1021/ol302034rDOI
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:23 Aug 2012 09:25
Last Modified:28 Sep 2012 10:06
Item ID:25743
Owner Only: item control page
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