Fredersdorf, Sabine and Thumann, Christian and Zimmermann, Wolfram H. and Vetter, Roland and Graf, Tobias and Luchner, Andreas and Riegger, Günter A. J. and Schunkert, Heribert and Eschenhagen, Thomas and Weil, Joachim (2012) Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data. Cardiovascular Diabetology 11, p. 57.
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Background Calcium (Ca2+) handling proteins are known to play a pivotal role in the pathophysiology of cardiomyopathy. However little is known about early changes in the diabetic heart and the impact of insulin treatment (Ins). Methods Zucker Diabetic Fatty rats treated with or without insulin (ZDF +/- Ins, n = 13) and lean littermates (controls, n = 7) were sacrificed at the age of 19 weeks. ...
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|Date:||23 May 2012|
|Institutions:||Medicine > Lehrstuhl für Innere Medizin II|
|Projects:||Open Access Publizieren (DFG)|
|Keywords:||Diabetic heart; Insulin; SERCA expression; Relaxation velocity|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Partially|
|Deposited On:||07 Sep 2012 07:00|
|Last Modified:||13 Mar 2014 19:11|