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Modelling the Genetic Risk in Age-Related Macular Degeneration

Grassmann, Felix and Fritsche, Lars G. and Keilhauer, Claudia N. and Heid, Iris M. and Weber, Bernhard H. F. (2012) Modelling the Genetic Risk in Age-Related Macular Degeneration. PloS ONE 7, e37979.

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Abstract

Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians. Besides age and smoking, genetic variants from several gene loci have reproducibly been associated with this condition and likely explain a large proportion of disease. Here, we developed a genetic risk score (GRS) for AMD based on 13 risk ...

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Item Type:Article
Date:30 May 2012
Institutions:Medicine > Lehrstuhl für Humangenetik
Medicine > Institut für Epidemiologie und Präventivmedizin
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0037979DOI
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Universitätsbibliothek Regensburg
Deposited On:07 Sep 2012 06:52
Last Modified:13 Mar 2014 19:12
Item ID:25862
Owner Only: item control page
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