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Neoimmun versus Neoral: a bioequivalence study in healthy volunteers and influence of a fat-rich meal on the bioavailability of Neoimmun

Kees, F. and Bucher, M. and Schweda, F. and Gschaidmeier, H. and Faerber, L. and Seifert, R. (2007) Neoimmun versus Neoral: a bioequivalence study in healthy volunteers and influence of a fat-rich meal on the bioavailability of Neoimmun. Naunyn-Schmiedeberg's Archives of Pharmacology 375 (6), pp. 393-399.

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Abstract

In two crossover studies with 12 (6 males/6 females) healthy young volunteers each, we compared the bioavailability of Neoimmun capsules with the microemulsion Neoral and the influence of a fat-rich breakfast on the bioavailability of Neoimmun. Each volunteer received a single dose of 200 mg cyclosporine A in each period. Blood samples were taken up to 24 h and analysed for cyclosporine A by ...

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Item Type:Article
Date:2007
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)
Identification Number:
ValueType
10.1007/s00210-007-0169-3UNSPECIFIED
Keywords:Cyclosporine A; Food effect; Bioavailability; Bioequivalence; Gender effect
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:28 Jan 2008 15:12
Last Modified:13 Mar 2014 10:20
Item ID:2665
Owner Only: item control page
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