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SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing

Dohm, Juliane C. ; Lottaz, Claudio ; Borodina, Tatiana ; Himmelbauer, Heinz



Zusammenfassung

The latest revolution in the DNA sequencing field has been brought about by the development of automated sequencers that are capable of generating giga base pair data sets quickly and at low cost. Applications of such technologies seem to be limited to resequencing and transcript discovery, due to the shortness of the generated reads. In order to extend the fields of application to de novo ...

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