Startseite UB

Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands.

Ziemek, Ralf and Brennauer, Albert and Schneider, Erich and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), pp. 10-8.

Full text not available from this repository.

at PubMed

at publisher (via DOI)

Other URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1J-4KV847D-C&_user=616165&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000032338&_version=1&_urlVersion=0&_userid=616165&md5=47bb600e84270bd013f9f53b22959195


Abstract

With respect to the discovery and characterization of neuropeptide Y(2) receptor ligands as pharmacological tools or potential drugs, fluorescence- and luminescence-based assays were developed to determine both the affinity and the activity of receptor agonists and antagonists. A flow cytometric binding assay is described for the hY(2) receptor stably expressed in CHO cells using cy5-labeled ...

plus


Export bibliographical data

Item Type:Article
Date:2006
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Dr. Chiara Cabrele
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
17027743PubMed ID
10.1016/j.ejphar.2006.08.075DOI
Keywords:Fluorescent probe; Neuropeptide Y; Y2 receptor; Flow cytometry; Chimeric G protein; Aequorin; BIIE0246
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:21 Feb 2008 08:22
Last Modified:05 Aug 2009 13:42
Item ID:3382
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact