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Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations

Oettl, Martin and Hoechstetter, Julia and Asen, Iris and Bernhardt, Günther and Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), pp. 267-277.

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Other URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T25-487F477-6&_user=616165&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000032338&_version=1&_urlVersion=0&_userid=616165&md5=93b97781a207a2a87d02099041c3d79f


Abstract

Although bovine testicular hyaluronidase (BTH) has been used in several medical fields for many years, these drugs are poorly characterized. We compared pharmaceutical BTH preparations (Neopermease®, Hylase® “Dessau”) and a hyaluronate lyase from Streptococcus agalactiae. The BTH preparations were complex mixtures of proteins (SDS–PAGE, gel filtration) with enzymatic activity in different ...

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Item Type:Article
Date:2003
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
10.1016/S0928-0987(03)00022-8DOI
Keywords:Bovine testicular hyaluronidase; Hyaluronate lyase; Streptococcus agalactiae; SDS–PAGE; Zymography; Limited proteolysis
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:21 Feb 2008 10:19
Last Modified:05 Aug 2009 13:42
Item ID:3396
Owner Only: item control page
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