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Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists

Zabel, Manfred and Breu, Josef and Rau, Franz and Range, Klaus-Jürgen and Krey, Volker and Uffrecht, Anka and Buschauer, Armin (2000) Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists. Acta Crystallographica Section C 56, pp. 250-251.

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Other URL: http://scripts.iucr.org/cgi-bin/paper?S0108270199014699


Abstract

The structural information gained from the study of the chiral building block (R)-(-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid-L-(-)-ephedrine [methyl(1-hydroxy-1-phenylprop-2-yl)ammonium 4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoate], C10H16NO+·C15H12Cl2NO2-, can be used to deduce the absolute configuration of highly potent arpromidine-type histamine H2 receptor agonists, as the chiral ...

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Item Type:Article
Date:2000
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
10.1107/S0108270199014699DOI
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:22 Feb 2008 08:31
Last Modified:05 Aug 2009 13:42
Item ID:3411
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