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Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE

Schuster, Andreas and Bernhardt, Günther and Eibler, Ernst and Buschauer, Armin and Hesselink, Willy (1998) Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE. Journal of Chromatography A 793 (1), pp. 77-90.

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Abstract

We present a high-performance liquid chromatography (HPLC) and a capillary zone electrophoresis (CZE) method for the chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, -guanidines and -guanidine-N-carboxylic acid esters. The N-alkoxycarbonylguanidines were resolved into enantiomers on a Chiralpak AD column with resolutions ≥2.0. The separation of chloro-substituted ...

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Item Type:Article
Date:1998
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
10.1016/S0021-9673(97)00848-0DOI
Keywords:Phenylpyridylpropylamines; Arpromidine; Guanidines; Histamine agonists
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:22 Feb 2008 13:26
Last Modified:05 Aug 2009 13:42
Item ID:3421
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