Seitz, Michael and Reiser, Oliver (2005) Synthetic Approaches towards structurally divers γ-Butyrolactone Natural Product-like Compounds. Current Opinion in Chemical Biology 9 (3), pp. 285-292.
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Other URL: http://dx.doi.org/10.1016/j.cbpa.2005.03.005
Natural products containing a γ-butyrolactone ring are abundant in nature; however, few general synthetic approaches to their stereoselective synthesis with broad structural variety are known. In this article, recent developments towards mono- and polycyclic γ-butyrolactone natural products and analogs are discussed. A special focus is given to asymmetric methods applying transition metal or organocatalysts that allow not only the efficient introduction of a broad variety of functional groups but ideally also the flexible construction of various natural-product-like, polycyclic scaffolds from common precursors.
|Institutions:||Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Owner:||Helge Knüttel (ADMIN)|
|Deposited On:||05 Sep 2006|
|Last Modified:||05 Aug 2009 13:22|