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Effects of L-Glutamate on auditory afferent activity in view of its proposed excitatory transmitter role in the mammalian cochlea

Gleich, Otto and Johnstone, Brian M. and Robertson, Donald (1990) Effects of L-Glutamate on auditory afferent activity in view of its proposed excitatory transmitter role in the mammalian cochlea. Hearing Research 45 (3), pp. 295-312.

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Abstract

This report describes the effects of L-glutamate (Glu) introduced into the perilymph of scala tympani on the spontaneous and tone-evoked activity of guinea pig single primary auditory afferents. Concentrations below 2 mmol/1 were in general ineffective, while a concentration of 5 mmol/1 caused a marked decrease of the neural activity. At 2 mmol/1, roughly 60% of the Glu-perfusions were effective ...

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Item Type:Article
Date:May 1990
Institutions:Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Keywords:Cochlea; Hair cell; Auditory afferents; Synapse; Transmitter; L-Glutamate
Subjects:500 Science > 590 Zoological sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Universitätsbibliothek Regensburg
Deposited On:27 May 2008 14:57
Last Modified:13 Mar 2014 10:27
Item ID:3709
Owner Only: item control page

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