Nishino, Y. and Schneider, M. R. and Michna, H. and Angerer, E. von (1991) Pharmacological characterization of a novel oestrogen antagonist, ZK 119010, in rats and mice. The Journal of endocrinology 130 (3), pp. 409-414.
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The oestrogenic and antioestrogenic effects of a new nonsteroidal compound ZK 119010 (2-(4-hydroxyphenyl)-3-methyl-1-[6-(1-pyrrolidinyl)-hexyl]-indol-5-ol) were evaluated and compared with those of tamoxifen and ICI 164384. In immature mice, ZK 119010 administered once daily for 3 days (s.c.) inhibited the uterotrophic and vaginotrophic effect of oestradiol in a dose-dependent manner and was ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Partially|
|Deposited On:||11 Dec 2008 16:56|
|Last Modified:||05 Aug 2009 13:48|