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Effect of zindoxifene on experimental prostatic tumours of the rat

Schneider, M. R. and Schiller, C. D. and Humm, A. and Angerer, E. von (1991) Effect of zindoxifene on experimental prostatic tumours of the rat. Journal of cancer research and clinical oncology 117 (1), pp. 33-36.

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Abstract

The anti-oestrogen zindoxifene was originally developed as a drug for the treatment of hormone-dependent mammary carcinomas. Experiments with rats bearing androgen-dependent prostatic tumours revealed anti-neoplastic activity of zindoxifene on these tumours also. Therefore, the inhibitory effect of this drug was studied in various prostatic tumour models in comparison to the anti-oestrogen ...

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Item Type:Article
Date:1991
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
ValueType
1997466PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
AnimalsMESH
Antineoplastic Agents/pharmacologyMESH
CastrationMESH
Diethylstilbestrol/pharmacologyMESH
Estrogen Antagonists/pharmacologyMESH
Indoles/pharmacologyMESH
MaleMESH
Neoplasm TransplantationMESH
Neoplasms, Experimental/drug therapyMESH
Neoplasms, Hormone-Dependent/drug therapyMESH
Prostatic Neoplasms/drug therapyMESH
RatsMESH
Rats, Inbred F344MESH
Tamoxifen/pharmacologyMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:03 Dec 2008 15:56
Last Modified:05 Aug 2009 13:48
Item ID:4751
Owner Only: item control page
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