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Dunning R3327-G prostate carcinoma of the rat: an appropriate model for drug evaluation

Kager, M. and Spruss, T. and Schneider, M. R. and Angerer, E. von (1992) Dunning R3327-G prostate carcinoma of the rat: an appropriate model for drug evaluation. Journal of cancer research and clinical oncology 118 (5), pp. 334-338.

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Models for testing new drugs for the treatment of hormone-dependent prostate cancer are restricted to a few in vivo rat tumour lines; most of them originating from the Dunning R3327 adenocarcinoma. The original tumour and the R3327-H line grow rather slowly leading to a long duration of therapeutic experiments. The R3327-G subline can be transplanted as a cell suspension or tumour fragments, ...


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Item Type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
1583064PubMed ID
Adenocarcinoma/drug therapyMESH
Androgen Antagonists/therapeutic useMESH
Disease Models, AnimalMESH
Drug Screening Assays, AntitumorMESH
Neoplasm TransplantationMESH
Prostatic Neoplasms/drug therapyMESH
Rats, Inbred F344MESH
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:10 Dec 2008 14:48
Last Modified:05 Aug 2009 13:48
Item ID:4753
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