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The effect of a combination of zindoxifene and cisplatin on Dunning R3327-G prostatic carcinomas of the rat

Angerer, E. von and Birnböck, H. and Kager, M. and Maucher, A. (1992) The effect of a combination of zindoxifene and cisplatin on Dunning R3327-G prostatic carcinomas of the rat. Journal of cancer research and clinical oncology 118 (5), pp. 339-343.

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Abstract

Endocrine therapy of hormone-dependent prostatic carcinomas can be very effective at the beginning. However, tumour growth eventually resumes possibly because of the presence of androgen-independent cell clones. Addition of a cytotoxic agent to the hormonally active drug at an early stage could possibly delay progression of disease. Therefore, we studied the effects of hormonal and cytostatic ...

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Item Type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
ValueType
1583065PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
AnimalsMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Cisplatin/administration & dosageMESH
Drug Screening Assays, AntitumorMESH
Estrogen Antagonists/administration & dosageMESH
Indoles/administration & dosageMESH
MaleMESH
Prostatic Neoplasms/drug therapyMESH
RatsMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:11 Dec 2008 17:11
Last Modified:05 Aug 2009 13:48
Item ID:4755
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