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Evaluation of the antitumour activity of coumarin in prostate cancer models

Maucher, A. and Kager, M. and Angerer, E. von (1993) Evaluation of the antitumour activity of coumarin in prostate cancer models. Journal of cancer research and clinical oncology 119 (3), pp. 150-154.

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Abstract

Responses to coumarin have been reported for patients suffering from malignant melanoma, metastatic renal carcinoma and, recently, advanced prostate cancer. These data together with some experimental evidence for antiprostatic effect prompted us to study the activity of coumarin in various prostate tumour models and evaluate the endocrine properties of this drug. In rats no antiandrogenic ...

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Item Type:Article
Date:1993
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
ValueType
8418087PubMed ID
10.1007/BF01229529DOI
Classification:
NotationType
AnimalsMESH
Antineoplastic Agents/therapeutic useMESH
Coumarins/therapeutic useMESH
Drug Administration ScheduleMESH
Drug Screening Assays, AntitumorMESH
Lung Neoplasms/prevention & controlMESH
MaleMESH
Neoplasm TransplantationMESH
OrchiectomyMESH
Prostatic Neoplasms/drug therapyMESH
RatsMESH
Rats, Inbred F344MESH
Tumor Cells, CulturedMESH
Keywords:Coumarin; Prostate carcinoma; Dunning R3327-G tumour; Noble tumour; Dunning R3327-MatLu tumour; Metastases
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:03 Dec 2008 15:54
Last Modified:05 Aug 2009 13:48
Item ID:4757
Owner Only: item control page
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