Maucher, A. and Angerer, E. von (1993) Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours. Journal of cancer research and clinical oncology 119 (11), pp. 669-674.
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The nonsteroidal antiandrogen casodex has been described as a peripherally selective drug for the treatment of prostatic cancer. In this study we determined its activity in various models of hormone-dependent malignancies including those of the prostate and the breast. Analysis of endocrine effects in rats after 15 days of treatment revealed a strong reduction of the weights of prostates and ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)|
|Keywords:||Nonsteroidal antiandrogen; LNCaP prostate carcinoma cells; Dunning R3327-G tumour; MXT mouse mammary tumour|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||01 Dec 2008 16:54|
|Last Modified:||05 Aug 2009 13:48|