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3-Substituierte 2-Phenylindole: Synthese und biologische Eigenschaften

Mahboobi, Siavosh and Grothus, Götz and von Angerer, Erwin (1994) 3-Substituierte 2-Phenylindole: Synthese und biologische Eigenschaften. Archiv der Pharmazie 327 (8), pp. 481-492.

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Abstract

3-Substituted 2-phenylindoles: synthesis and biological properties. Knoevenagel-reaction of indol-3-carbaldehydes 5a,b and 7a,b with nitromethane leads to the nitroethenes 12 and 14, the analogous reaction with malodinitrile to the methylidenemalonic acid dinitriles 16.- Michael-addition of nitromethane at 12 and 14 affords the 1,3-dinitropropanes 13 and 15, reduction of 16 the methylmalonic ...

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Item Type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
7944904PubMed ID
Classification:
NotationType
Antineoplastic Agents/chemical synthesisMESH
HumansMESH
Indoles/chemical synthesisMESH
Receptors, Estrogen/drug effectsMESH
Structure-Activity RelationshipMESH
Tumor Cells, CulturedMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:16 Jan 2009 09:40
Last Modified:05 Aug 2009 13:48
Item ID:4760
Owner Only: item control page
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