Startseite UB

The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP

Bouchal, Jan and Kolár, Zdenek and Mad'arová, Jana and Hlobilková, Alice and Angerer, Erwin von (2002) The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP. Biochemical Pharmacology 63 (6), pp. 1177-81.

Full text not available from this repository.

at PubMed


Abstract

The effects of the 17beta-estradiol, dihydrotestosterone and hormone antagonists tamoxifen and bicalutamide on telomerase activity and expression of cell cycle related proteins in the androgen-sensitive prostatic cancer cell line LNCaP were studied. The cell line was grown in RPMI supplemented with 2.5% charcoal-stripped FBS for 72 hr. The IC(50) of tamoxifen and bicalutamide and the optimal ...

plus


Export bibliographical data

Item Type:Article
Date:2002
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
11931851PubMed ID
Classification:
NotationType
Androgens/metabolismMESH
Antineoplastic Agents, Hormonal/pharmacologyMESH
Dihydrotestosterone/pharmacologyMESH
Estradiol/pharmacologyMESH
HumansMESH
ImmunoblottingMESH
LigandsMESH
MaleMESH
Prostatic Neoplasms/enzymologyMESH
Receptors, Pancreatic Hormone/antagonists & inhibitorsMESH
Tamoxifen/pharmacologyMESH
Telomerase/drug effectsMESH
Tumor Cells, CulturedMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Prof. Armin Buschauer
Deposited On:03 Dec 2008 15:38
Last Modified:05 Aug 2009 13:48
Item ID:4777
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact